Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes

• Main Authors: Lianhua He (Author), Huijie Luan (Author), Juan He (Author), Miaomiao Zhang (Author), Qingxia Qin (Author), Yiping Hu (Author), Yueming Cai (Author), Desheng Sun (Author), Yu Shi (Author), Qingwen Wang (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rheumatoid arthritis is a progressive and systemic autoimmune disease seriously compromises human health. Fibroblast like synoviocytes are the major effectors of proliferation and inflammation in rheumatoid arthritis synovial tissue. Shikonin has anti-inflammatory and immunomodul...