Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury

• Egile Nagusiak: Haoyang Ma (Egilea), Jiaye Liu (Egilea), Yang Du (Egilea), Shengnan Zhang (Egilea), Weidong Cao (Egilea), Zhanjun Jia (Egilea), Wei Gong (Egilea), Aihua Zhang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Sepsis-associated liver dysfunction remains a challenge in clinical practice with high mortality and limited specific therapies. DY131 is a pharmacological agonist of the orphan receptor estrogen-related receptor (ERR) γ which plays a crucial role in regulating energy generation, oxidative metabolis...