Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury

• Autori principali: Haoyang Ma (Autore), Jiaye Liu (Autore), Yang Du (Autore), Shengnan Zhang (Autore), Weidong Cao (Autore), Zhanjun Jia (Autore), Wei Gong (Autore), Aihua Zhang (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Sepsis-associated liver dysfunction remains a challenge in clinical practice with high mortality and limited specific therapies. DY131 is a pharmacological agonist of the orphan receptor estrogen-related receptor (ERR) γ which plays a crucial role in regulating energy generation, oxidative metabolis...