Dynamics of receptor-operated Ca2+ Currents Through TRPC Channels Controlled via the PI(4,5)P2-PLC Signaling Pathway

• Main Authors: Masayuki X Mori (Author), Kyohei eItsuki (Author), Hideharu eHase (Author), Seishirou eSawamura (Author), Tatsuki eKurokawa (Author), Yasuo eMori (Author), Ryuji eInoue (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transient receptor potential canonical (TRPC) channels are Ca2+-permeable, nonselective cation channels that carry receptor-operated Ca2+ currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). Within the vascula...