Evaluation of the Effect of Food on the Pharmacokinetics of SHR6390, An Oral CDK4/6 Inhibitor, in Healthy Volunteers

• 主要な著者: Yan-ping Liu (著者), Ming-hui Hu (著者), Ping-ping Lin (著者), Ting Li (著者), Shu-qin Liu (著者), Yu-ya Wang (著者), Shao-rong Li (著者), Xiang-kun Li (著者), Chen-jing Wang (著者), Yu Cao (著者)
• フォーマット: 図書
• 出版事項: Adis, Springer Healthcare, 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background and Introduction SHR6390 is a new developed highly effective and selective small-molecule oral CDK4/6 inhibitor. We aimed to evaluate the effect of food on the pharmacokinetics of SHR6390 tablets. Methods In an open-label two-way crossover study, 24 healthy Chinese volunteers wer...