Losartan Normalizes Endothelium-Derived Hyperpolarizing Factor-Mediated Relaxation by Activating Ca2+-Activated K+ Channels in Mesenteric Artery From Type 2 Diabetic GK Rat
Ca2+-activated K+ (K Ca ) channels are important for endothelium-derived hyperpolarizing factor (EDHF) signaling. Since treatment with angiotensin II receptor blockers (ARBs) improves vasculopathies in type 2 diabetic patients, we asked whether the EDHF-type relaxation and its associated K Ca channe...
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| Main Authors: | , , , , |
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| Format: | Book |
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Elsevier,
2010-01-01T00:00:00Z.
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