Population pharmacokinetic analysis and dosing regimen optimization of teicoplanin in critically ill patients with sepsis

• Main Authors: Chao‐Yang Chen (Author), Min Xie (Author), Jun Gong (Author), Ning Yu (Author), Ran Wei (Author), Li‐Li Lei (Author), Si‐Miao Zhao (Author), Ruo‐Ming Li (Author), Xiu Dong (Author), Xiang‐Lin Zhang (Author), Ying Zhou (Author), Shuang‐Ling Li (Author), Yi‐Min Cui (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Teicoplanin has been extensively used in the treatment for infections caused by gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). However, current teicoplanin treatment is challenging due to relatively low and variable concentrations under standard dosa...