Oxidative Stress and Neurodegeneration: Interconnected Processes in PolyQ Diseases
Neurodegenerative polyglutamine (polyQ) disorders are caused by trinucleotide repeat expansions within the coding region of disease-causing genes. PolyQ-expanded proteins undergo conformational changes leading to the formation of protein inclusions which are associated with selective neuronal degene...
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2021-09-01T00:00:00Z.
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