Investigating the effect of dehydromiltirone on septic AKI using a network pharmacology method, molecular docking, and experimental validation

• Автори: Sijia Chen (Автор), Yanzhe Wang (Автор), Yuyuan Liu (Автор), Linnan Bai (Автор), Fengqin Li (Автор), Yue Wu (Автор), Xinmiao Xie (Автор), Nan Zhang (Автор), Chuchu Zeng (Автор), Ling Zhang (Автор), Xiaoxia Wang (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Acute kidney injury (AKI) is a severe and frequent complication of sepsis that occurs in intensive care units with inflammation and rapid decline in renal function as the main pathological features. Systemic inflammation, microvascular dysfunction, and tubule injury are the main causes of sepsis-ind...