Machine Learning Quantification of Amyloid Deposits in Histological Images of Ligamentum Flavum

• Main Authors: Andy Y. Wang (Author), Vaishnavi Sharma (Author), Harleen Saini (Author), Joseph N. Tingen (Author), Alexandra Flores (Author), Diang Liu (Author), Mina G. Safain (Author), James Kryzanski (Author), Ellen D. McPhail (Author), Knarik Arkun (Author), Ron I. Riesenburger (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Wild-type transthyretin amyloidosis (ATTRwt) is an underdiagnosed and potentially fatal disease. Interestingly, ATTRwt deposits have been found to deposit in the ligamentum flavum (LF) of patients with lumbar spinal stenosis before the development of systemic and cardiac amyloidosis. In order to stu...