SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation

• Päätekijät: Mingzhu Jiang (Tekijä), Min Zhao (Tekijä), Mi Bai (Tekijä), Juan Lei (Tekijä), Yanggang Yuan (Tekijä), Songming Huang (Tekijä), Yue Zhang (Tekijä), Guixia Ding (Tekijä), Zhanjun Jia (Tekijä), Aihua Zhang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Karger Publishers, 2021-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background: Podocyte injury contributes to progressive glomerulosclerosis. Previously, we demonstrated the important role of the NLR family pyrin domain containing 3 (NLRP3) inflammasome in mediating the podocyte injury induced by aldosterone. Silent mating type information regulation 2 homolog 1 (S...