SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation

Background: Podocyte injury contributes to progressive glomerulosclerosis. Previously, we demonstrated the important role of the NLR family pyrin domain containing 3 (NLRP3) inflammasome in mediating the podocyte injury induced by aldosterone. Silent mating type information regulation 2 homolog 1 (S...

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Main Authors: Mingzhu Jiang (Author), Min Zhao (Author), Mi Bai (Author), Juan Lei (Author), Yanggang Yuan (Author), Songming Huang (Author), Yue Zhang (Author), Guixia Ding (Author), Zhanjun Jia (Author), Aihua Zhang (Author)
Format: Book
Published: Karger Publishers, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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