Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat

• Asıl Yazarlar: Kazuhiko Seya (Yazar), Zaiqiang Yu (Yazar), Kouta Kanemaru (Yazar), Kazuyuki Daitoku (Yazar), Yui Akemoto (Yazar), Hiroyuki Shibuya (Yazar), Ikuo Fukuda (Yazar), Ken Okumura (Yazar), Shigeru Motomura (Yazar), Ken-Ichi Furukawa (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2011-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Although aging is well established as an important risk factor for aortic stenosis, the mechanism of age-related aortic valve calcification is yet unknown. Here, we investigated this mechanism in tissue and cellular levels using middle-aged rats. Aortic valve specimens were obtained by dissecting fr...