Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat

Although aging is well established as an important risk factor for aortic stenosis, the mechanism of age-related aortic valve calcification is yet unknown. Here, we investigated this mechanism in tissue and cellular levels using middle-aged rats. Aortic valve specimens were obtained by dissecting fr...

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Main Authors: Kazuhiko Seya (Author), Zaiqiang Yu (Author), Kouta Kanemaru (Author), Kazuyuki Daitoku (Author), Yui Akemoto (Author), Hiroyuki Shibuya (Author), Ikuo Fukuda (Author), Ken Okumura (Author), Shigeru Motomura (Author), Ken-Ichi Furukawa (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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