A mild phenotype associated with KCNQ1 p.V205M mediated long QT syndrome in First Nations children of Northern British Columbia: effect of additional variants and considerations for management

• Main Authors: Simona Bene Watts (Author), Barbara Gauthier (Author), Anders C. Erickson (Author), Julie Morrison (Author), Mavis Sebastian (Author), Lawrence Gillman (Author), Sarah McIntosh (Author), Connie Ens (Author), Elizabeth Sherwin (Author), Rod McCormick (Author), Shubhayan Sanatani (Author), Laura Arbour (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionCongenital Long QT Syndrome (LQTS) is common in a First Nations community in Northern British Columbia due to the founder variant KCNQ1 p.V205M. Although well characterized molecularly and clinically in adults, no data have been previously reported on the pediatric population. The phenot...