Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Survival

• Main Authors: Prativa Sahoo (Author), Paul Frankel (Author), Julie Ressler (Author), Margarita Gutova (Author), Alexander J. Annala (Author), Behnam Badie (Author), Jana Portnow (Author), Karen S. Aboody (Author), Massimo D'Apuzzo (Author), Russell C. Rockne (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The aim of this study was to correlate T1-weighted dynamic contrast-enhanced MRI- (DCE-MRI-) derived perfusion parameters with overall survival of recurrent high-grade glioma patients who received neural stem cell- (NSC-) mediated enzyme/prodrug gene therapy. Methods. A total of 12 patie...