Integrated top-down and bottom-up proteomics mass spectrometry for the characterization of endogenous ribosomal protein heterogeneity

• Main Authors: Ying Zhang (Author), Qinghua Cai (Author), Yuxiang Luo (Author), Yu Zhang (Author), Huilin Li (Author)
• 格式: 图书
• 出版: Elsevier, 2023-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Ribosomes are abundant, large RNA-protein complexes that are the sites of all protein synthesis in cells. Defects in ribosomal proteins (RPs), including proteoforms arising from genetic variations, alternative splicing of RNA transcripts, post-translational modifications and alterations of protein e...