Development of a non-infectious control for viral hemorrhagic fever PCR assays.

• Prif Awduron: Matthew A Knox (Awdur), Collette Bromhead (Awdur), David Ts Hayman (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Public Library of Science (PLoS), 2024-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Assay validation is an essential component of disease surveillance testing, but can be problematic in settings where access to positive control material is limited and a safety risk for handlers. Here we describe a single non-infectious synthetic control that can help develop and validate the PCR ba...