Antioxidant Effects of Stereoisomers of N-Acetylcysteine (NAC), L-NAC and D-NAC, on Angiotensin II-Stimulated MAP Kinase Activation and Vascular Smooth Muscle Cell Proliferation

• Main Authors: Moe Kyaw (Author), Masanori Yoshizumi (Author), Koichiro Tsuchiya (Author), Yuki Izawa (Author), Yasuhisa Kanematsu (Author), Yoshiko Fujita (Author), Nermin Ali (Author), Keisuke Ishizawa (Author), Aiko Yamauchi (Author), Toshiaki Tamaki (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined the effects of the stereoisomers of N-acetylcysteine (NAC), L-NAC and D-NAC, on cellular glutathione (GSH) concentration and whether NAC-regulated cellular GSH levels are directly associated with angiotensin II (Ang II)-induced intracellular signaling events in vascular smooth muscle cel...