Radiosynthesis, structural identification and in vitro tissue binding study of [18F]FNA-S-ACooP, a novel radiopeptide for targeted PET imaging of fatty acid binding protein 3

• Main Authors: Pyry Dillemuth (Author), Tuomas Karskela (Author), Abiodun Ayo (Author), Jesse Ponkamo (Author), Jonne Kunnas (Author), Johan Rajander (Author), Olli Tynninen (Author), Anne Roivainen (Author), Pirjo Laakkonen (Author), Anu J. Airaksinen (Author), Xiang-Guo Li (Author)
• Format: Book
• Published: SpringerOpen, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fatty acid binding protein 3 (FABP3) is a target with clinical relevance and the peptide ligand ACooP has been identified for FABP3 targeting. ACooP is a linear decapeptide containing a free amino and thiol group, which provides opportunities for conjugation. This work is to deve...