Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

Treatment of patients with triple-negative breast cancer (TNBC) is challenging due to the absence of well- defined molecular targets and the heterogeneity of such disease. In our endeavor to develop potent isatin-based anti-proliferative agents, we utilized the hybrid-pharmacophore approach to synth...

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Main Authors: Wagdy M. Eldehna (Author), Hadia Almahli (Author), Ghada H. Al-Ansary (Author), Hazem A. Ghabbour (Author), Mohamed H. Aly (Author), Omnia E. Ismael (Author), Abdullah Al-Dhfyan (Author), Hatem A. Abdel-Aziz (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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