NMDA Receptor-Antagonistic Properties of Hyperforin, a Constituent of St. John's Wort

• Main Authors: Vikas Kumar (Author), Alexander Mdzinarishvili (Author), Cornelia Kiewert (Author), Thomas Abbruscato (Author), Ulrich Bickel (Author), Cornelis J. van der Schyf (Author), Jochen Klein (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracts of the medicinal plant St. John's wort (Hypericum perforatum) are widely used for the treatment of affective disorders. Hyperforin, a constituent of St. John's wort, is known to modulate the release and re-uptake of various neurotransmitters, an action that likely underlies its an...