Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis. The drugs ivermectin, diethylcarbamazine (DEC), and albendazole are used in control programs for these diseases, but are mainly effective against t...
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Public Library of Science (PLoS),
2015-02-01T00:00:00Z.
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A1234.567 |
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