Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action

• Main Authors: Srinivas Angapelly (Author), P. V. Sri Ramya (Author), Rohini Sodhi (Author), Andrea Angeli (Author), Krishnan Rangan (Author), Narayana Nagesh (Author), Claudiu T. Supuran (Author), Mohammed Arifuddin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A practical and transition metal-free one-pot domino synthesis of diversified (1,3,4-oxadiazol-2-yl)anilines has been developed employing isatins and hydrazides as the starting materials, in the presence of molecular iodine. The prominent feature of this domino process involves consecutive condensat...