Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling

• 主要な著者: Xuemin Gao (著者), Dingjie Xu (著者), Shumin Li (著者), Zhongqiu Wei (著者), Shifeng Li (著者), Wenchen Cai (著者), Na Mao (著者), Fuyu Jin (著者), Yaqian Li (著者), Xue Yi (著者), Heliang Liu (著者), Hong Xu (著者), Fang Yang (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2020-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied the effects of this disease on the expression of microRNAs (miRNAs) in the lung. Rattus norvegicus pulmonary silicosis models were used in conjunction with high-throughput screening of lung specimens to co...