Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival

• Egile Nagusiak: Zhengtai Chen (Egilea), Chenxi Zhang (Egilea), Haiwei Ma (Egilea), Zihuai Huang (Egilea), Jiafeng Li (Egilea), Junshen Lou (Egilea), Baolong Li (Egilea), Qi Tu (Egilea), Weiyang Gao (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Multiterritory perforator flap survival is commonly applied in surgical tissue reconstructions and covering of large skin defects. However, multiple risk factors such as ischemia, reperfusion injury, and apoptosis after reconstructive surgeries cause necrosis in distal parts with outcomes ranging fr...