Evaluation of adverse events focusing on infection associated with infliximab originator and biosimilar using a spontaneous reporting system database

• Main Authors: Iku Niinomi (Author), Keiko Hosohata (Author), Yasuhiro Mori (Author), Yuki Yamaguchi (Author), Tomohito Wakabayashi (Author), Mayako Uchida (Author), Kazunori Iwanaga (Author)
• Format: Book
• Published: BMC, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Infliximab (IFX) has changed the management of many life-threatening immune-mediated diseases. The high cost of IFX and its patent expiry have led to pharmaceutical companies developing a biosimilar; however, its safety profile remains unknown in the real world. The purpose of th...