Small Molecule Drugs Targeting Viral Polymerases

• Main Authors: Deborah Palazzotti (Author), Martina Sguilla (Author), Giuseppe Manfroni (Author), Violetta Cecchetti (Author), Andrea Astolfi (Author), Maria Letizia Barreca (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small molecules that specifically target viral polymerases-crucial enzymes governing viral genome transcription and replication-play a pivotal role in combating viral infections. Presently, approved polymerase inhibitors cover nine human viruses, spanning both DNA and RNA viruses. This review provid...