High resolution melting: improvements in the genetic diagnosis of hypertrophic cardiomyopathy in a Portuguese cohort

• Main Authors: Santos Susana (Author), Marques Vanda (Author), Pires Marina (Author), Silveira Leonor (Author), Oliveira Helena (Author), Lança Vasco (Author), Brito Dulce (Author), Madeira Hugo (Author), Esteves J Fonseca (Author), Freitas António (Author), Carreira Isabel M (Author), Gaspar Isabel M (Author), Monteiro Carolino (Author), Fernandes Alexandra R (Author)
• Format: Book
• Published: BMC, 2012-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hypertrophic Cardiomyopathy (HCM) is a complex myocardial disorder with a recognized genetic heterogeneity. The elevated number of genes and mutations involved in HCM limits a gene-based diagnosis that should be considered of most im...