Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective

Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective

Angiotensin-converting enzyme (ACE), a zinc metalloprotein, is a central component of the renin-angiotensin system (RAS). It degrades bradykinin and other vasoactive peptides. Angiotensin-converting-enzyme inhibitors (ACE inhibitors, ACEIs) decrease the formation of angiotensin II and increase the l...

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Bibliographic Details
Main Authors: Wenyue Zheng (Author), Erkang Tian (Author), Zhen Liu (Author), Changhan Zhou (Author), Pei Yang (Author), Keyue Tian (Author), Wen Liao (Author), Juan Li (Author), Changyu Ren (Author)
Format: Book
Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
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