Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

• Главные авторы: Dolf Segers (Автор), Jonathan A. Lipton (Автор), Pieter J. M. Leenen (Автор), Caroline Cheng (Автор), Dennie Tempel (Автор), Gerard Pasterkamp (Автор), Frans L. Moll (Автор), Rini de Crom (Автор), Rob Krams (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2011-01-01T00:00:00Z.
• Предметы: article
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Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE-/- mice, we induced unstable plaque with using...