Mingmu Xiaoyao granules regulate the PI3K/Akt/mTOR signaling pathway to reduce anxiety and depression and reverse retinal abnormalities in rats

• Main Authors: Qiuyan Ma (Author), Jian Zhou (Author), Ziyi Yang (Author), Yuxin Xue (Author), Xinran Xie (Author), Tiejun Li (Author), Yingxin Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate the effects of Mingmu Xiaoyao granules (MMXY) on the morphology and function of the retina and the mechanism of PI3K/Akt/mTOR pathway-related proteins in rats with anxiety and depression induced by chronic unpredictable mild stress (CUMS).Methods: Fifty-two male Sprague Daw...