Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides

• Main Authors: Azzurra Stefanucci (Author), Andrea Angeli (Author), Marilisa Pia Dimmito (Author), Grazia Luisi (Author), Sonia Del Prete (Author), Clemente Capasso (Author), William A. Donald (Author), Adriano Mollica (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Six tripeptides incorporating acidic amino acid residues were prepared for investigation as activators of β- and γ-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacteria Vibrio cholerae, Mycobacterium tuberculosis, and Burkholderia pseudomallei. The primary amino acid residues that are i...