Functional single nucleotide polymorphisms in dopaminergic receptors D2 predict clinical response to Cariprazine

• Main Authors: Marco De Pieri (Author), Marco Ferrari (Author), Franca Marino (Author), Rafael Traber (Author), Emilio Bolla (Author), Marco Cosentino (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Cariprazine (CAR) is an antipsychotic drug for the treatment of schizophrenia (SCZ) and bipolar disorder (BD), and it acts as a partial agonist on the dopamine receptors (DR), D2, and D3. Although many single nucleotide polymorphisms (SNPs) in genes coding for these receptors are known to influence...