Inhibition of MurA Enzyme from <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> by Diterpenes from <i>Lepechinia meyenii</i> and Their Synthetic Analogs

• Autores principales: Macarena Funes Chabán (Autor), Martina Hrast (Autor), Rok Frlan (Autor), Dafni G. Graikioti (Autor), Constantinos M. Athanassopoulos (Autor), María Cecilia Carpinella (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2021-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Enzymes MurA and MurF, involved in bacterial cell wall synthesis, have been validated as targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes and synthetic analogs derived therefrom were investigated for their inhibitory properties on these enzymes from &l...