Formulation and evaluation of transdermal drug-delivery system of isosorbide dinitrate

• Main Authors: Xiaoping Zhan (Author), Zhenmin Mao (Author), Sijing Chen (Author), Shaoxiong Chen (Author), Liqun Wang (Author)
• Format: Book
• Published: Universidade de São Paulo, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>The purpose of this study was to develop a reservoir-type transdermal delivery system for isosorbide dinitrate (ISDN). The developed patch consisted of five layers from bottom to top, namely, a temporary liner, an adhesive layer, a rate-controlling membrane, a reservoir and a backing. The e...