Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells

• Main Authors: Jui-Ting Chang (Author), Yao-Jen Liang (Author), Chia-Yu Hsu (Author), Chao-Yi Chen (Author), Po-Jung Chen (Author), Yi-Feng Yang (Author), Yen-Lin Chen (Author), Dee Pei (Author), Jin-Biou Chang (Author), Jyh-Gang Leu (Author)
• Format: Book
• Published: BMC, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hyperglycemia-induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) production play major roles in progression of diabetic nephropathy. Anti-RAGE effect of peroxisome proliferator-activated receptor-delta (PPARδ) agonists was shown in previous studies. PPARδ...