Acylation of the antimicrobial peptide CAMEL for cancer gene therapy

• Päätekijät: Jingjing Song (Tekijä), Panpan Ma (Tekijä), Sujie Huang (Tekijä), Juanli Wang (Tekijä), Huan Xie (Tekijä), Bo Jia (Tekijä), Wei Zhang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Obtaining ideal gene delivery vectors is still a major goal in cancer gene therapy. CAMEL, a short hybrid antimicrobial peptide, can kill cancer cells by membrane lysis. In this study, we constructed a series of non-viral vectors by attaching fatty acids with different chain lengths to the N-terminu...