Acylation of the antimicrobial peptide CAMEL for cancer gene therapy

• Asıl Yazarlar: Jingjing Song (Yazar), Panpan Ma (Yazar), Sujie Huang (Yazar), Juanli Wang (Yazar), Huan Xie (Yazar), Bo Jia (Yazar), Wei Zhang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Obtaining ideal gene delivery vectors is still a major goal in cancer gene therapy. CAMEL, a short hybrid antimicrobial peptide, can kill cancer cells by membrane lysis. In this study, we constructed a series of non-viral vectors by attaching fatty acids with different chain lengths to the N-terminu...