Acylation of the antimicrobial peptide CAMEL for cancer gene therapy

• मुख्य लेखकों: Jingjing Song (लेखक), Panpan Ma (लेखक), Sujie Huang (लेखक), Juanli Wang (लेखक), Huan Xie (लेखक), Bo Jia (लेखक), Wei Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Obtaining ideal gene delivery vectors is still a major goal in cancer gene therapy. CAMEL, a short hybrid antimicrobial peptide, can kill cancer cells by membrane lysis. In this study, we constructed a series of non-viral vectors by attaching fatty acids with different chain lengths to the N-terminu...