Pharmacological inhibition of STAT3 by BP‐1‐102 inhibits intracranial aneurysm formation and rupture in mice through modulating inflammatory response

• Asıl Yazarlar: Zhixian Jiang (Yazar), Jiaxin Huang (Yazar), Lingtong You (Yazar), Jinning Zhang (Yazar), Bingyu Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2021-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract As an inhibitor of STAT3, BP‐1‐102 can regulate the inflammation response caused by vascular smooth muscle cells (VSMCs) by inhibiting the JAK/STAT3/NF‐κB pathway, thereby attenuating the symptoms of intracranial aneurysm (IA). IA mouse model was established by stereotactic injection of ela...