Tablet Disintegratability: Sensitivity of Superdisintegrants to Temperature and Compaction Pressure

• Main Authors: Audrey Yi Zheng (Author), Paul Wan Sia Heng (Author), Lai Wah Chan (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Tablet disintegration is an important pre-requisite for drug dissolution and absorption. The disintegration test is typically conducted at 37 °C, but the intragastric temperature may vary due to meals or fever. This study investigated the effects of temperature and compaction pressure on tablet disi...