Enhancing Intradermal Delivery of Lidocaine by Dissolving Microneedles: Comparison between Hyaluronic Acid and Poly(Vinyl Pyrrolidone) Backbone Polymers

• Main Authors: Delly Ramadon (Author), Lissa Florencia Putri Sutrisna (Author), Yahdiana Harahap (Author), Kurnia Sari Setio Putri (Author), Fathin Ulayya (Author), Pietradewi Hartrianti (Author), Qonita Kurnia Anjani (Author), Ryan F. Donnelly (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lidocaine hydrochloride (LiH), an amide-type local anesthetic agent, is commonly used in dermatological procedures. LiH is categorized as a BCS (biopharmaceutics classification system) class III group, which has high solubility and poor permeability. It should be noted that, in this context, LiH is...