A PAM of the α1A-Adrenergic receptor rescues biomarker, long-term potentiation, and cognitive deficits in Alzheimer's disease mouse models without effects on blood pressure

α1-Adrenergic Receptors (ARs) regulate the sympathetic nervous system by the binding of norepinephrine (NE) and epinephrine (Epi) through different subtypes (α1A, α1B, α1D). α1A-AR activation is hypothesized to be memory forming and cognitive enhancing but drug development has been stagnant due to u...

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Main Authors: Robert S. Papay (Author), Shaun R. Stauffer (Author), Dianne M. Perez (Author)
Format: Book
Published: Elsevier, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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