Predict drug sensitivity of cancer cells with pathway activity inference

Abstract Background Predicting cellular responses to drugs has been a major challenge for personalized drug therapy regimen. Recent pharmacogenomic studies measured the sensitivities of heterogeneous cell lines to numerous drugs, and provided valuable data resources to develop and validate computati...

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Main Authors: Xuewei Wang (Author), Zhifu Sun (Author), Michael T. Zimmermann (Author), Andrej Bugrim (Author), Jean-Pierre Kocher (Author)
Format: Book
Published: BMC, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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