Concept and utility of population pharmacokinetic and pharmacokinetic/pharmacodynamic models in drug development and clinical practice

• Main Authors: Roganović Maša (Author), Homšek Ana (Author), Jovanović Marija (Author), Topić-Vučenović Valentina (Author), Ćulafić Milica (Author), Miljković Branislava (Author), Vučićević Katarina (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Due to frequent clinical trial failures and consequently fewer new drug approvals, the need for improvement in drug development has, to a certain extent, been met using model-based drug development. Pharmacometrics is a part of pharmacology that quantifies drug behaviour, treatment response and dise...