Concept and utility of population pharmacokinetic and pharmacokinetic/pharmacodynamic models in drug development and clinical practice

• Автори: Roganović Maša (Автор), Homšek Ana (Автор), Jovanović Marija (Автор), Topić-Vučenović Valentina (Автор), Ćulafić Milica (Автор), Miljković Branislava (Автор), Vučićević Katarina (Автор)
• Формат: Книга
• Опубліковано: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2021-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Due to frequent clinical trial failures and consequently fewer new drug approvals, the need for improvement in drug development has, to a certain extent, been met using model-based drug development. Pharmacometrics is a part of pharmacology that quantifies drug behaviour, treatment response and dise...