Mechanisms of action of Sappan lignum for prostate cancer treatment: network pharmacology, molecular docking and experimental validation

• Main Authors: Wenna Li (Author), Honglin Jiang (Author), Weina Zhang (Author), Qiuyue Sun (Author), Qiaoli Zhang (Author), Jingnan Xu (Author), Jinchang Huang (Author), Yuxiang Wan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundProstate cancer (PCa) is the most common non-cutaneous malignancy in men globally. Sappan lignum, which exists in the heartwood of Caesalpinia sappan L., has antitumor effects; however, its exact mechanism of action remains unclear. This study elucidated the underlying mechanisms of Sappan...