Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner

• Main Authors: Kaikai Zhang (Author), Lijian Chen (Author), Jianzheng Yang (Author), Jiali Liu (Author), Jiahao Li (Author), Yi Liu (Author), Xiuwen Li (Author), Long Chen (Author), Clare Hsu (Author), Jiahao Zeng (Author), Xiaoli Xie (Author), Qi Wang (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methamphetamine (Meth) abuse can cause serious mental disorders, including anxiety and depression. The gut microbiota is a crucial contributor to maintaining host mental health. Here, we aim to investigate if microbiota participate in Meth-induced mental disorders, and the potential mechanisms invol...