α-Synuclein Toxicity in <i>Drosophila melanogaster</i> Is Enhanced by the Presence of Iron: Implications for Parkinson's Disease

• Główni autorzy: Francesco Agostini (Autor), Luigi Bubacco (Autor), Sasanka Chakrabarti (Autor), Marco Bisaglia (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by the preferential loss of dopaminergic neurons and by the accumulation of intracellular inclusions mainly composed of α-synuclein (α-Syn). While the etiopathogenesis of the disorder is still elusive,...