Metformin Reverses <i>tmexCD1-toprJ1</i>- and <i>tet</i>(A)-Mediated High-Level Tigecycline Resistance in <i>K. pneumoniae</i>

• मुख्य लेखकों: Xia Xiao (लेखक), Quanmin Huan (लेखक), Yanhu Huang (लेखक), Yuan Liu (लेखक), Ruichao Li (लेखक), Xilan Xu (लेखक), Zhiqiang Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tigecycline (TIG) is one of the last effective options against multidrug resistance bacteria. Recently, the RND (resistance-nodulation-division) efflux pump gene cluster, <i>tmexCD1-toprJ1</i>, and the tetracycline-efflux pump <i>tet</i>(A) mutation were reported to mediate h...