Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs

• Main Authors: Jan Bures (Author), Ilja Tacheci (Author), Jaroslav Kvetina (Author), Vera Radochova (Author), Darina Kohoutova (Author), Martin Valis (Author), Stanislav Rejchrt (Author), Veronika Knoblochova (Author), Jana Zdarova Karasova (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Galantamine has been used as a treatment for Alzheimer disease. It has a unique, dual mode of action (inhibitor of acetylcholinesterase and allosteric modulator of nicotinic acetylcholine receptors). Nausea (in about 20%), vomiting (10%) and diarrhoea (5-7%) are the most common side effects. The aim...