Gastric floating sustained-release tablet for dihydromyricetin: Development, characterization, and pharmacokinetics study

• Main Authors: Hao Liu (Author), Wenmei Zhao (Author), Qi Hu (Author), Ling Zhao (Author), Yumeng Wei (Author), Chao Pi (Author), Yuhan Yang (Author), Xuerong Yang (Author), Hang Yuan (Author), Yuhan Zhang (Author), Kunyan Qu (Author), Xinyu Shi (Author), Yao Huang (Author), Houyin Shi (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dihydromyricetin (DHM) is a natural dihydroflavonol compound with quite a number of important pharmacological properties. However, its low solubility in water and poor stability in aqueous environment, have compromised drug efficacy of DHM, thus hindering its clinical use. The present study was to d...