EZH2 Knockdown Upregulates Expression of the Genes Involved in T-ALL Cell Differentiation

• Main Authors: Sahar Safaei (Author), Behzad Baradaran (Author), Behzad Mansoori (Author), Masoumeh Fardi (Author), Elham Baghbani (Author), Mohammad Amini (Author), Nima Hemmat (Author), Elham Safarzadeh (Author), Mahdi Abdoli Shadbad (Author), Dariush Shanehbandi (Author), Saeed Solali (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), as one of the polycyclic group proteins (PcGs), is an epigenetic regulator that plays a crucial role in the pathophysiology of hematologic malignancies through regulating cell differentiation. Also, it is well known that a...