Seeing the Trees From the Forest: Challenges in Subgroup Analysis-Based Guidelines in Oncology

• Main Authors: Ofer Rotem (Author), Karyn Revital Geiger (Author), Ekaterina Hanovich (Author), Mor Moskovitz (Author), Noga Kurman (Author), Daniel Reinhorn (Author), Idit Peretz (Author), Rinat Yerushalmi (Author), Salomon M. Stemmer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As clinical trials in oncology require substantial efforts, maximizing the insights gained from them by conducting subgroup analyses is often attempted. The goal of these analyses is to identify subgroups of patients who are likely to benefit, as well as the subgroups of patients who are unlikely to...