Evaluation of Placental Transfer and Tissue Distribution of cis- and Trans-Permethrin in Pregnant Rats and Fetuses Using a Physiological-Based Pharmacokinetic Model

• Main Authors: Stéphane Personne (Author), Céline Brochot (Author), Paulo Marcelo (Author), Aurélie Corona (Author), Sophie Desmots (Author), Franck Robidel (Author), Anthony Lecomte (Author), Véronique Bach (Author), Florence Zeman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Biomonitoring studies have highlighted the exposure of pregnant women to pyrethroids based on the measurement of their metabolites in urine. Pyrethroids can cross the placental barrier and be distributed in the fetus as some pyrethroids were also measured in the meconium of newborns. Prenatal exposu...